Adaptive changes in neuronal receptive fields under multiple contexts
Dates:1 January 2017 - 31 March 2017
Date limite de candidature:1 January 2017
Lab rotation proposal: 3 months
~ Jan-March 2017 ~ Apr-June 2017
We propose to study how cortical receptive fields can be rapidly reshaped by behavioral conditioning. We will use two-photon fluorescence microscopy to record neuronal activity with cellular resolution in anaesthetized and in awake mice. We will focus on adaptive plasticity in receptive fields of neurons in A1 (the primary auditory cortex), and explore how classical conditioning for a single tone can change the receptive field properties of both inhibitory interneurons and excitatory pyramidal cells in layers I, to III of the cortex. This is a collaborative project between our group and Dr. Shihab Shamma’s group at the DEC department (ENS). These experiments will provide a better understanding of the cellular basis of adaptive neuronal changes during classical conditioning, and also yield new insights into the effects of learning and reward on early sensory processing.
Address: IBENS - École Normale Supérieure - 46, Rue d’Ulm 75005 Paris
Phone number: +33 1 44 32 37 34 ; Email: firstname.lastname@example.org