Neural stem cells and regeneration in the retina
Dates:1 September 2016 - 30 June 2017
Date limite de candidature:1 September 2016
Lab rotation proposal:
~ Sep-Dec 2016 ~ Jan-March 2017 ~ Apr-June 2017
Degenerative retinal diseases ultimately lead to blindness due to photoreceptor loss. One curative strategy would be to stimulate neural tissue repair through the mobilization of quiescent stem cells. However, the successful therapeutic exploitation of endogenous retinal stem cells of patients primarily requires elucidation of the molecular mechanisms controlling their behavior. In this context, our laboratory is taking advantage of two complementary animal models, the mouse and the frog, two vertebrate species with active and quiescent retinal stem cells, respectively. Our lab is investigating how signaling pathways and intrinsic factors work in concert to finely regulate the balance between quiescence and proliferation in physiological and neurodegenerative conditions.
Address: Neuroscience Paris-Saclay Institute Neuropsi - Bâtiment 145, Centre D'études De Saclay 91191 Gif Sur Yvette
Phone number: +33 1 69 15 72 25 ; Email: email@example.com