PICNIC Lab Physiological Investigations of Clinically Normal & Impaired Cognition

Research center

47 bld de l'Hôpital
75651 Paris
Alexis Brice


Université Pierre et Marie Curie
Université Paris 6
Université Pierre et Marie Curie


UMRS 1127 UMR 7225


Faugeras F, Naccache L. Dissociating temporal attention from spatial attention and motor response preparation: A high-density EEG study. Neuroimage. 2016 Jan 1;124(Pt A):947-57. doi: 10.1016/j.neuroimage.2015.09.051. Epub 2015 Oct 1. Erratum in: Neuroimage. 2016 Feb 15;127():512.

Rohaut B, Faugeras F, Chausson N, King JR, Karoui IE, Cohen L, Naccache L. Probing ERP correlates of verbal semantic processing in patients with impaired consciousness.Neuropsychologia. 2015 Jan;66:279-92. doi: 10.1016/j.neuropsychologia.2014.10.014. Epub 2014 Nov 22.

Sharman M, Gallea C, Lehongre K, Galanaud D, Nicolas N, Similowski T, Cohen L, Straus C, Naccache L. The cerebral cost of breathing: an FMRI case-study in congenital central hypoventilation syndrome. PLoS One. 2014 Sep 30;9(9):e107850. doi: 10.1371/journal.pone.0107850. eCollection 2014.

Salti M, El Karoui I, Maillet M, Naccache L. Cognitive dissonance resolution is related to episodic memory. PLoS One. 2014 Sep 29;9(9):e108579. doi: 10.1371/journal.pone.0108579. eCollection 2014.

El Karoui I, King JR, Sitt J, Meyniel F, Van Gaal S, Hasboun D, Adam C, Navarro V, Baulac M, Dehaene S, Cohen L, Naccache L. Event-Related Potential, Time-frequency, and Functional Connectivity Facets of Local and Global Auditory Novelty Processing: An Intracranial Study in Humans. Cereb Cortex. 2014 Jun 26. pii: bhu143.

Rohaut B, Faugeras F, Chausson N, King JR, Karoui IE, Cohen L, Naccache L. Probing ERP correlates of verbal semantic processing in patients with impaired consciousness. Neuropsychologia. 2015 Jan;66:279-92. doi: 10.1016/j.neuropsychologia.2014.10.014. Epub 2014 Nov 22.

Martinaud O, Pouliquen D, Gerardin E, Loubeyre M, Hirsbein D, Hannequin D, Cohen L (2012) Visual agnosia and posterior cerebral artery infarcts: an anatomical-clinical study. ploS One 7:e30433.

Faugeras F, Rohaut B, Weiss N, Bekinschtein T, Galanaud D, Puybasset L, Bolgert F, Sergent C, Cohen L, Dehaene S, Naccache L (2012) Event related potentials elicited by violations of auditory regularities in patients with impaired consciousness. Neuropsychologia 50:403-418.

Bouvier G, Laviolette L, Kindler F, Naccache L, Mouraux A, Similowski T, Morelot-Panzini C (2012) Dyspnea-pain counter-irritation induced by inspiratory threshold loading: a laser evoked potentials study. J Appl Physiol. 2011

King JR, Bekinschtein T, Dehaene S (2011) Comment on "Preserved feedforward but impaired top-down processes in the vegetative state". Science 334:1203 5. Vinckier F, Qiao E, Pallier C, Dehaene S, Cohen L (2011) The impact of letter spacing on reading: A test of the bigram coding hypothesis. J Vis 11:1-21.

Fields of research

Cognitive neurosciences / neuropsychology /neuroeconomy

Research Theme

The PICNIC lab is devoted to the study of cognitive functions with an exclusive or prevalent development in humans, namely language and conscious cognition. The study of brain-damaged patients occupies a central position in our methodological approach. For the study of both language and consciousness, and with both patients and healthy subjects, we resort to state-of-the-art behavioural methods and multimodal brain imaging (MRI, high-density surface EEG and intracerebral implanted electrodes). In the field of language, we mostly address the brain mechanisms of reading a domain which gives an empirical grasp on the interplay of cultural phenomena and biological background. Our main project concerns the dynamics of word reading: functioning, origins, and impairments. We address questions such as: how are visual words encoded and recognized in adults? how do word recognition abilities emerge from the interaction of education and of the pre-existing biological background? what are the functional abnormalities underlying acquired reading impairments, and what are the compensation mechanisms that may develop in such conditions? In the field of consciousness, we aim at discovering the specific psychological and neural properties of conscious processing, by contrasting conscious and unconscious cognition, both in healthy subjects and in patients in comatose, vegetative or  inimally conscious states. Particularly we probe in such patients the depth of cognitive processing in the domain of semantics, short-term memory, and strategic elaboration. Beyond fundamental issues, we also derive tools for the assessment or rehabilitation of patients. Thus we recently demonstrated the value of ERPs for assessing the diagnosis and prognosis of comatose patients.

Etudiants ENP


Membres de l'équipe