Optogenetic analysis of astrocyte gliotransmission
Dates:1 September 2016 - 1 December 2016
Date limite de candidature:1 September 2016
Lab rotation proposal: 3 months
~ Sep-Dec 2016 ~ Jan-March 2017 ~ Apr-June 2017
Address: Neurophysiology and New Microscopies Laboratory - Université Paris Descartes - 45, rue des Saints Pères 75006 Paris
Phone number: +33 1 42 86 41 54 ; Email: firstname.lastname@example.org
Our team has recently implemented an optogenetic approach to manipulate the activity of astrocytes in the hippocampus and the cortex of the mouse. The aim is to analyze the impact of astrocyte release of transmitters on neurons in the healthy and epileptic brain. During this lab rotation, the student will participate to experiments combining this approach with slice electrophysiology and 2-photon imaging.